Introduction: Traditional Chinese Medicine (TCM) is a complementary and alternative medical system which has been included in the eleventh revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-11). Ample evidence shows TCM is effective for the treatment of various intractable and chronic diseases.

Objective: To share experiences in the use of TCM in the treatment for intractable and chronic diseases.

Methodology: This is a case series report of four intractable chronic diseases successfully treated with acupuncture and food therapy based on TCM diagnosis.

Results: Case 1 is a 26-year-old female with chronic intractable constipation. TCM diagnosis was dual deficiency of heart Qi and blood pattern (ICD-11: SF62). Treatment by acupuncture and TCM food therapy relieved the constipation in one month. Case 2 is a 60-year-old male with progressive diabetic nephropathy. TCM diagnosis was dampness-heat encumbering the spleen system pattern (ICD-11: SF78). Treatment by acupuncture and TCM food therapy decreased the blood glycosylated haemoglobin and creatinine concentrations. Case 3 is a 38-year-old male with chronic intractable hemorrhoids. TCM diagnosis was spleen Qi sinking pattern (ICD-11: SF71). Treatment by TCM food therapy relieved the hemorrhoids in two months. Case 4 is a female with progressive dyspnea after recovering from COVID-19 a year prior. One session of TEAS effectively relieved severe dyspnea. No adverse effects were reported by all the patients.

Conclusion: TCM is a safe, simple, and effective treatment for various intractable chronic diseases.