Asian Journal of Complementary and Alternative Medicine

Asian Journal of Complementary and Alternative Medicine

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Effect of β-Glucan (Angel Yeast) Compared to a Placebo on Cold and Flu Incidence and Symptoms in an Adult Population – A Double Blind, Randomised Controlled Trial

David Briskey1,2 and Amanda Rao1*

1RDC Clinical, Newstead, Brisbane, 4006, QLD, Australia
2School of Human Movement and Nutrition Sciences, University of Queensland, Brisbane, 4067, QLD Australia


Background: β-1, 3/1, 6-glucan derived from Baker’s yeast (Saccharomyces cerevisiae) is a widely studied and documented β-glucan known for its immune stimulatory efficacy, mode of action, and safety. Previous research indicates that it may have an effect on reducing symptoms of cold and flu. The current study aimed to examine the effects of yeast β-glucan (Angel Yeast) on cold and flu incidences and symptoms in a healthy adult population.

Methods: Two hundred and thirty-one males and females aged between 18 and 65 years old completed 3 months of supplementation with either β-glucan or a placebo. Participants completed a general health questionnaire throughout the trial period and recorded any incidences of cold and flu symptoms.

Results: β-glucan supplementation reduced the self-reported severity of sore throats and improved sleep quality.

Conclusions: Yeast β-glucan was shown to be safe and tolerable, with results indicating it can reduce the severity of a sore throat experienced during a cold or flu episode. 

Yeast β-glucan; Saccharomyces cerevisiae; Upper respiratory tract infection
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